CHROMOSOMAL LOCALIZATION OF THE HUMAN CILIARY NEUROTROPHIC FACTOR GENE (CNTF) TO 11Q12 BY FLUORESCENCE INSITU HYBRIDIZATION

被引：13

作者：

GIOVANNINI, M

ROMO, AJ

EVANS, GA

机构：

[1] Molecular Genetics I aboratory, The Salk Institute for Biological Studies, La Jolla, CA

来源：

CYTOGENETICS AND CELL GENETICS | 1993年 / 63卷 / 01期

关键词：

D O I：

10.1159/000133504

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The human gene for ciliary neurotrophic factor (CNTF) was previously assigned to chromosome 11 by analysis of a panel of somatic cell hybrids. We isolated cosmid clones containing the CNTF gene from an arrayed-chromosome specific library and used fluorescent in situ hybridization to regionally localize the human CNTF gene on chromosome 11. The gene maps at an FLpter of 0.46, corresponding to a cytogenetic band position of 11q12.2.

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页码：62 / &

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