IDENTIFICATION BY ANTIIDIOTYPE ANTIBODIES OF AN INTRACELLULAR MEMBRANE-PROTEIN THAT RECOGNIZES A MAMMALIAN ENDOPLASMIC-RETICULUM RETENTION SIGNAL

被引：234

作者：

VAUX, D

TOOZE, J

FULLER, S

机构：

[1] EUROPEAN MOLEC BIOL LAB,BIOL STRUCT PROGRAMME,MEYERHOFSTR 1,W-6900 HEIDELBERG,GERMANY

[2] EUROPEAN MOLEC BIOL LAB,CELL BIOL PROGRAMME,W-6900 HEIDELBERG,GERMANY

来源：

NATURE | 1990年 / 345卷 / 6275期

关键词：

D O I：

10.1038/345495a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Monoclonal antibodies were raised against antibodies to distinct carboxy-terminal KDEL sequences of two soluble, resident endoplasmic reticulum proteins. These anti-idiotype reagents recognize an intrinsic membrane protein with characteristics expected of a receptor responsible for the recognition and return of resident proteins to the endoplasmic reticulum. © 1990 Nature Publishing Group.

引用

页码：495 / 502

页数：8

共 37 条

[1]

BALCH WE, 1986, J BIOL CHEM, V261, P4681

[2] TRANSFER OF PROTEINS ACROSS MEMBRANES .2. RECONSTITUTION OF FUNCTIONAL ROUGH MICROSOMES FROM HETEROLOGOUS COMPONENTS [J].