TRANSLOCATION (16-21)(P11-Q22) IN ACUTE MONOBLASTIC LEUKEMIA WITH ERYTHROPHAGOCYTOSIS

被引：19

作者：

MAROSI, C

BETTELHEIM, P

GEISSLER, K

LECHNER, K

KOLLER, U

HAAS, OA

CHOTT, A

HAGEMEIJER, A

机构：

[1] ST ANNA CHILDRENS HOSP,CCRI,VIENNA,AUSTRIA

[2] ERASMUS UNIV,DEPT CELL BIOL & GENET,3000 DR ROTTERDAM,NETHERLANDS

[3] UNIV VIENNA,INST IMMUNOL,A-1090 VIENNA,AUSTRIA

[4] UNIV VIENNA,INST PATHOL,A-1090 VIENNA,AUSTRIA

来源：

CANCER GENETICS AND CYTOGENETICS | 1991年 / 54卷 / 01期

关键词：

D O I：

10.1016/0165-4608(91)90030-X

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A patient with acute monoblastic leukemia with erythrophagocytosis and a t(16;21) (p11;q22), poor response to chemotherapy, early relapse, and a short survival of ten months is presented. Hematologically, this patient could be considered as a case of FAB M5b/t(8;16) but without the characteristic chromosomal translocation, i.e., there is no visible alteration on chromosome 8 and the breakpoint on chromosome 16 appears to be very proximal. These findings are briefly discussed in the light of other variants.

引用

页码：61 / 66

页数：6

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