OXIDATIVE-METABOLISM OF SPIRONOLACTONE - EVIDENCE FOR THE INVOLVEMENT OF ELECTROPHILIC THIOSTEROID SPECIES IN DRUG-MEDIATED DESTRUCTION OF RAT HEPATIC CYTOCHROME-P450

被引:37
作者
DECKER, CJ
RASHED, MS
BAILLIE, TA
MALTBY, D
CORREIA, MA
机构
[1] UNIV CALIF SAN FRANCISCO,DEPT PHARMACOL,BOX 0450,SAN FRANCISCO,CA 94143
[2] UNIV CALIF SAN FRANCISCO,CTR LIVER,SAN FRANCISCO,CA 94143
关键词
D O I
10.1021/bi00438a033
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:5128 / 5136
页数:9
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