Temporal Trends in Incidence and Case Fatality of Intracerebral Hemorrhage: The Tromso Study 1995-2012

被引:24
作者
Carlsson, Maria [1 ,4 ]
Wilsgaard, Tom [2 ]
Johnsen, Stein Harald [1 ,3 ]
Vangen-Lonne, Anne Merete [1 ,5 ]
Lochen, Maja-Lisa [2 ]
Njolstad, Inger [2 ]
Mathiesen, Ellisiv Bogeberg [1 ,3 ]
机构
[1] UiT, Dept Clin Med, Tromso, Norway
[2] UiT, Dept Community Med, Tromso, Norway
[3] Univ Hosp North Norway, Dept Neurol & Clin Neurophysiol, Tromso, Norway
[4] Nordland Hosp, Dept Neurol, Mailbox 1480, NO-8092 Bodo, Norway
[5] Innlandet Hosp Trust, Dept Neurol, Lillehammer, Norway
关键词
Intracerebral hemorrhage; Stroke incidence; Cohort study; Epidemiology;
D O I
10.1159/000447719
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Background: The aim of this study was to explore temporal trends in incidence and case fatality rates of intracerebral hemorrhage (ICH) over the last two decades in a Norwegian municipality. Methods: Incident cases of primary ICH were registered in the period from 1995 through 2012 in 32,530 participants of the longitudinal population-based Tromso Study. Poisson regression models were used to obtain incidence rates over time in age-and sex-adjusted and age- and sex-specific models. Case fatality rates were calculated and age- and sex adjusted trends over time were estimated using logistic regression. Results: A total of 226 ICHs were registered. The age- and sex-adjusted incidence rate [95% confidence interval (CI)] in the overall population was 0.42 (0.37-0.48) per 1,000 person-years. Age-adjusted incidence rates were 0.53 (0.43-0.62) in men and 0.33 (0.26-0.39) in women. In individuals aged <75 years, the age- and sex-adjusted incidence rate was 0.27 (0.22-0.32) and in individuals aged 75 years, it was 2.42 (1.95-2.89) per 1,000 person-years. There was no significant change in incidence rates over time. The incidence rate ratio (95% CI) in the overall population was 0.73 (0.47-1.12) in 2012 compared with 1995. The overall 30-day case fatality (95% CI) was 23.9% (18.3-29.5) and did not change substantially over time [odds ratio in 2012 vs. 1995 = 0.83 (95% CI 0.27-2.52)]. Conclusion: No significant changes in incidence and case fatality rates of ICH were observed during the last two decades. (C) 2016 The Author(s) Published by Karger AG, Basel
引用
收藏
页码:40 / 49
页数:10
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