FLOW-CYTOMETRY MEASUREMENT OF NUCLEAR-RNA CONTENT IN UVEAL MELANOMA

被引：4

作者：

CHEN, TC

CHAR, DH

WALDMAN, F

JUSTER, RP

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT OPHTHALMOL,CLIN ONCOL UNIT,POB 0730,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,CELL ANAL LAB,SAN FRANCISCO,CA 94143

[3] UNIV CALIF SAN FRANCISCO,FRANCIS J PROCTOR FDN,SAN FRANCISCO,CA 94143

[4] UNIV CALIF SAN FRANCISCO,DEPT RADIAT ONCOL,SAN FRANCISCO,CA 94143

来源：

OPHTHALMIC RESEARCH | 1990年 / 22卷 / 03期

关键词：

flow cytometry; nuclear RNA; uveal melanoma; prognosis; cell type;

D O I：

10.1159/000267022

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

We retrospectively studied the nuclear RNA content in uveal melanomas with known, long-term follow-up. Thirty patients had spindle cell melanomas, 25 had mixed cell tumors, and 9 had epithelioid cell neoplasms. Epithelioid cell types had a higher nuclear RNA content compared to mixed or spindle cell types (p < 0.05). Using the Cox proportional hazards model, the nuclear RNA content appeared to be an independent prognostic indicator in uveal melanomas, and an increased nuclear RNA content was associated with a worse prognosis (p = 0.001).

引用

页码：187 / 193

页数：7

共 50 条

[41] IMPROVING THE PROGNOSTIC VALUE OF DNA FLOW-CYTOMETRY IN METASTATIC MELANOMA BY COMBINING PLOIDY AND S-PHASE FRACTION
MUHONEN, T
MELANOMA RESEARCH, 1992, 2 (04) : 247 - 252
[42] STEREOLOGICALLY MEASURED NUCLEAR VOLUME IN COMPARISON TO 2-DIMENSIONAL NUCLEAR MORPHOMETRY, MITOTIC INDEX AND FLOW-CYTOMETRY IN PREDICTING DISEASE OUTCOME IN BLADDER-CANCER
LIPPONEN, PK
ANTICANCER RESEARCH, 1993, 13 (02) : 529 - 532
[43] Comparison of nuclear DNA content of citrus rootstock populations by flow cytometry analysis
Seker, M
Tuzcu, O
Ollitrault, P
PLANT BREEDING, 2003, 122 (02) : 169 - 172
[44] Estimation of nuclear DNA content of cultivated Ocimum species by using flow cytometry
Koroch, Adolfina R.
Wang, Wenqin
Michael, Todd P.
Dudai, Nativ
Simon, James E.
Belanger, Faith C.
ISRAEL JOURNAL OF PLANT SCIENCES, 2010, 58 (3-4) : 183 - 189
[45] Nuclear DNA content of Solanum species grown in vitro, as determined by flow cytometry
Maciejewska, U
Skierski, JS
Szczerbakowa, A
ACTA PHYSIOLOGIAE PLANTARUM, 1999, 21 (01) : 37 - 43
[46] Analysis of nuclear DNA content in Capsicum (Solanaceae) by flow cytometry and Feulgen densitometry
Moscone, EA
Baranyi, M
Ebert, I
Greilhuber, J
Ehrendorfer, F
Hunziker, AT
ANNALS OF BOTANY, 2003, 92 (01) : 21 - 29
[47] Nuclear DNA content of Solanum species grown in vitro, as determined by flow cytometry
Urszula Maciejewska
Janusz S. Skierski
Anna Szczerbakowa
Acta Physiologiae Plantarum, 1999, 21 : 37 - 43
[48] SIMULTANEOUS MEASUREMENT, USING FLOW-CYTOMETRY, OF RADIOSENSITIVITY AND DEFECTIVE MITOGEN RESPONSE IN ATAXIA TELANGIECTASIA AND RELATED SYNDROMES
SEYSCHAB, H
SCHINDLER, D
FRIEDL, R
BARBI, G
BOLTSHAUSER, E
FRYNS, JP
HANEFELD, F
KORINTHENBERG, R
KRAGELOHMANN, I
SCHERES, JMJC
SCHINZEL, A
SEEMANOVA, E
TOMMERUP, N
HOEHN, H
EUROPEAN JOURNAL OF PEDIATRICS, 1992, 151 (10) : 756 - 760
[49] TESTICULAR SEMINOMA - CLINICAL-SIGNIFICANCE OF NUCLEAR DEOXYRIBONUCLEIC-ACID PLOIDY PATTERN AS STUDIED BY FLOW-CYTOMETRY
MOR, Y
LEIBOVICH, I
RAVIV, G
NASS, D
MEDALIA, O
GOLDWASSER, B
NATIV, O
JOURNAL OF UROLOGY, 1995, 154 (03) : 1041 - 1043
[50] Nuclear DNA content and genome size estimation of Stevia rebaudiana using flow cytometry
Yadav, A. K.
Singh, S.
Bhardwaj, G.
MINERVA BIOTECNOLOGICA, 2014, 26 (03) : 143 - 148

← 1 2 3 4 5 →