HEPATIC-UPTAKE OF IN-111 LABELED MONOCLONAL-ANTIBODIES - A SPECIFIC OR NONSPECIFIC EVENT

被引:0
|
作者
PIMM, MV
机构
来源
NUC COMPACT-EUROPEAN-AMERICAN COMMUNICATIONS IN NUCLEAR MEDICINE | 1990年 / 21卷 / 04期
关键词
IN-111; MONOCLONAL ANTIBODIES; HEPATIC UPTAKE;
D O I
暂无
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
One of the problems associated with the use of In-111 labelled monoclonal antibodies for immunoscintigraphy is the relatively high levels of tracer accumulated in the liver. Although the use of different chelators can partly overcome this problem, other factors may operate to cause hepatic clearance of monoclonal antibodies which, with radiometal as the label, is manifest as higher liver levels of the tracer.
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页码:155 / 157
页数:3
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