DETECTION OF SOMATOTROPIN RECEPTORS ON HUMAN MONOCYTES

被引：11

作者：

JAFARI, P

KHANSARI, DN

机构：

[1] N DAKOTA STATE UNIV,DEPT VET SCI MICROBIOL,FARGO,ND 58105

[2] IMMUNOBIOL LABS INC,NEW YORK,NY

来源：

IMMUNOLOGY LETTERS | 1990年 / 24卷 / 03期

关键词：

Growth hormone; Monocyte; Receptor; Somatotropin;

D O I：

10.1016/0165-2478(90)90048-U

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The expression of somatotropin receptors on human peripheral blood monocytes was investigated. Binding of [125] somatotropin to human monocytes was found to be specific and saturable. The binding was rapid and time-dependent, and was abolished by pretreatment of monocytes with trypsin. Scatchard plot analysis revealed that each cell bore more than 8×103 binding sites with an affinity constant of 1×108 M-1. © 1990.

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页码：199 / 202

页数：4

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