ENDOCRINE ABNORMALITIES IN THALASSEMIA MAJOR

被引：138
作者：
COSTIN, G
KOGUT, MD
HYMAN, CB
ORTEGA, JA
机构：
[1] CHILDRENS HOSP, DIV ENDOCRINOL & METAB, LOS ANGELES, CA 90027 USA
[2] UNIV SO CALIF, SCH MED, DEPT PEDIAT, LOS ANGELES, CA 90007 USA
[3] CHILDRENS HOSP, DIV HEMATOL ONCOL, LOS ANGELES, CA 90027 USA
来源：
AMERICAN JOURNAL OF DISEASES OF CHILDREN | 1979年 / 133卷 / 05期
关键词：
D O I：
10.1001/archpedi.1979.02130050041009
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Endocrine function evaluations in 16 patients with .beta.-thalassemia indicate that hypogonadotropic hypogonadism, hypoparathyroidism and reduced ACTH reserve occur frequently, whereas reduced growth hormone and thyroid reserve are less common manifestations. Hemosiderosis-induced damage of the endocrine glands seems to be the main cause for endocrine dysfunction in the patients studied.
引用
收藏
页码：497 / 502
页数：6
相关论文
共 31 条
[21]   MYOCARDIAL HEMOSIDEROSIS IN HYPOXIC MICE [J].
NECHELES, TF ;
BEARD, MEJ ;
ALLEN, DM .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1969, 165 (A1) :167-&
[22]   INTENSIVE TRANSFUSION THERAPY IN THALASSEMIA MAJOR - 8-YEAR FOLLOW-UP [J].
NECHELES, TF ;
CHUNG, S ;
SABBAH, R ;
WHITTEN, D .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1974, 232 (MAY24) :179-185
[23]   HYPERTRANSFUSION REGIMEN IN PATIENTS WITH COOLEYS ANEMIA [J].
PIOMELLI, S ;
KARPATKIN, MH ;
ARZANIAN, M ;
ZAMANI, M ;
BECKER, MH ;
GENEISER, N ;
DANOFF, SJ ;
KUHNS, WJ .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1974, 232 (MAY24) :186-192
[24]  
SALMON WD, 1957, J LAB CLIN MED, V49, P825
[25]   PITUITARY FUNCTION IN HAEMOCHROMATOSIS [J].
STOCKS, AE ;
MARTIN, FIR .
AMERICAN JOURNAL OF MEDICINE, 1968, 45 (06) :839-&
[26]  
TANKANO K, 1977, J CLIN ENDOCR METAB, V45, P828
[27]  
TANNER JM, 1962, GROWTH ADOLESCENCE, P33
[28]   MANAGEMENT OF THALASSEMIA - A COMPARATIVE PROGRAM [J].
WOLFF, JA ;
LUKE, KH .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1969, 165 (A1) :423-&
[29]   SOME CLINICAL FEATURES OF COOLEYS ANEMIA PATIENTS AS RELATED TO TRANSFUSION SCHEDULES [J].
WOLMAN, IJ ;
ORTOLANI, M .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1969, 165 (A1) :407-&
[30]  
WOLMAN IJ, 1964, ANN NY ACAD SCI, V119, P736
1234