Patients (16) whose chief complaint was ocular or periocular pain were diagnosed as having occipital neuritis. All but 1 had significant relief of pain from one or more injections of an anesthetic in the vicinity of the greater occipital nerve. They were subsequently treated with anti-inflammatory measures. From these cases definitions of significant tenderness and success of treatment were developed. These observations form a basis for a current double-blind study designed to establish a relationship between ocular pain and occipital neuritis.