FIRST ENANTIOSELECTIVE SYNTHESIS OF MIKANECIC ACID VIA DIELS-ALDER CYCLOADDITION MEDIATED CONSTRUCTION OF CHIRAL VINYLIC QUATERNARY CENTER

被引：32

作者：

BASAVAIAH, D

PANDIARAJU, S

SARMA, PKS

机构：

[1] School of Chemistry, University of Hyderabad, Hyderabad

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 24期

关键词：

D O I：

10.1016/S0040-4039(00)73158-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral mikanecic acid (1) was synthesized in 74% enantiomeric purity (92% ee after crystallization) via asymmetric Diels-Alder reaction of a novel in situ generated chiral 1,3-butadiene-2-carboxylate (A).

引用

页码：4227 / 4230

页数：4

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