The Many Flavors of Model-Based Meta-Analysis: Part I-Introduction and Landmark Data

被引：35
作者：
Boucher, M. [1 ]
Bennetts, M. [1 ]
机构：
[1] Pfizer Ltd, Pharmacometr, Sandwich, Kent, England
来源：
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY | 2016年 / 5卷 / 02期
关键词：
D O I：
10.1002/psp4.12041
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Meta-analysis is an increasingly important aspect of drug development as companies look to benchmark their own compounds with the competition. There is scope to carry out a wide range of analyses addressing key research questions from preclinical through to postregistration. This set of tutorials will take the reader through key model-based meta-analysis (MBMA) methods with this first installment providing a general introduction before concentrating on classical and Bayesian methods for landmark data.
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页码：54 / 64
页数：11
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