Two benzylated dihydroflavonols from Cudrania tricuspidata

被引：24

作者：

Lee, IK

Kim, CJ

Song, KS

Kim, HM

Yoo, ID

Koshino, H

Esumi, Y

Uramoto, M

机构：

[1] KOREA RES INST BIOSCI & BIOTECHNOL,TAEJON 305600,SOUTH KOREA

[2] RIKEN,INST PHYS & CHEM RES,WAKO,SAITAMA 35101,JAPAN

[3] TAMAGAWA UNIV,FAC AGR,MACHIDA,TOKYO 194,JAPAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1995年 / 58卷 / 10期

关键词：

D O I：

10.1021/np50124a024

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new benzylated dihydroflavonols, gericudranins D [1] and E [2], were isolated from the stem bark of Cudrania tricuspidata, and were identified as 5,7,4'-trihydroxy-6,8-di-p-hydroxybenzyldihydroflavonol and 5,7,4'-tridhydroxy-6-p-hydroxybenzyldihydroflavonol, respectively. These compounds were shown to be significantly cytotoxic to human tumor cell line in culture such as CRL 1579 (skin), LOX-IMVI (skin), MOLT-4F (leukemia), KM12 (colon), and UO-31 (renal).

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页码：1614 / 1617

页数：4

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