A METHOD FOR CALCULATING THE MEAN TRANSIT TIMES AND DISTRIBUTION RATE PARAMETERS OF METABOLITES WITHOUT SEPARATE INTRAVENOUS ADMINISTRATION OF METABOLITE

被引：5
作者：
CHENG, HY
机构：
[1] Department of Drug Metabolism Merck, Sharp & Dohme Research Laboratories, Pennsylvania
来源：
JOURNAL OF PHARMACEUTICAL SCIENCES | 1992年 / 81卷 / 05期
关键词：
D O I：
10.1002/jps.2600810522
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：488 / 490
页数：3
相关论文
共 17 条
[1]   MEAN RESIDENCE TIME IN THE BODY VERSUS MEAN RESIDENCE TIME IN THE CENTRAL COMPARTMENT [J].
BENET, LZ .
JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1985, 13 (05) :555-558
[2]  
BURKE JT, 1982, J PHARMACOKINET BIOP, V6, P601
[3]  
CHAN KK, 1982, DRUG METAB DISPOS, V10, P474
[4]   AN AREA FUNCTION-METHOD FOR CALCULATING THE APPARENT ELIMINATION RATE-CONSTANT OF A METABOLITE [J].
CHENG, HY ;
JUSKO, WJ .
JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1989, 17 (01) :125-130
[5]  
DELANNOY IAM, 1987, DRUG METAB DISPOS, V15, P51
[6]  
DELANNOY IAM, 1986, DRUG METAB DISPOS, V14, P513
[7]  
GIBALDI M, 1982, PHARMACOKINETICS, P25
[8]   DEFINITIONS AND APPLICATIONS OF MEAN TRANSIT AND RESIDENCE TIMES IN REFERENCE TO THE 2-COMPARTMENT MAMMILLARY PLASMA-CLEARANCE MODEL [J].
KONG, AN ;
JUSKO, WJ .
JOURNAL OF PHARMACEUTICAL SCIENCES, 1988, 77 (02) :157-165
[9]  
PANG KS, 1984, DRUG METAB DISPOS, V12, P309
[10]  
PANG KS, 1980, DRUG METAB DISPOS, V8, P39
12