METASTATIC ADENOCARCINOMA OF THE SPINE

被引：14

作者：

SAENGNIPANTHKUL, S

JIRARATTANAPHOCHAI, K

ROJVIROJ, S

SIRICHATIVAPEE, W

MAHAKKANUKRAUH, C

机构：

[1] Department of Orthopedic and Rehabilitation Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen

来源：

SPINE | 1992年 / 17卷 / 04期

关键词：

ADENOCARCINOMA OF SPINE; METASTASIS; SPINAL TUMOR;

D O I：

10.1097/00007632-199204000-00008

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Eighty-six patients presenting with metastatic adenocarcinoma of the spine were retrospectively reviewed. Forty-nine patients had neurologic compromise: paraplegia developed in 23 patients and loss of anal or urethral sphincter control occurred in 17 patients. Anterior decompression was performed in 35 patients and posterior decompression in 14 patients. The rest of the patients were treated nonoperatively. Neurologic recovery in the operated cases was unsatisfactory. We found that this particular histologic type of spinal metastasis is highly invasive and aggressive. Survival analysis in 74 evaluable patients showed a median survival time of 76 days, which was not affected by the presence of multiple lesions or neurologic compromise. Surgical decompression had no positive impact on survival of the patients. Therefore, it is suggested that nonoperative treatment should be the guideline, and operative treatment should be offered only to carefully selected cases of metastatic adenocarcinoma of the spine.

引用

页码：427 / 430

页数：4

共 15 条

[1]

Boland P.J., Lane J.M., Sundaresan N., Metastatic disease of the spine, Clin Orthop, 169, pp. 95-102, (1982)

[2]

Breslow N., A generalized Kruskal-Wallis test for comparing K samples subject to unequal patterns of censorship, Biometrika, 57, pp. 579-594, (1970)

[3]

Fermont J.C., Malignant cervical lymphadenopathy due to an unknown primary, Clin Radiol, 31, pp. 355-358, (1980)

[4]

Galasko C., Skeletal metastases, Clin Orthop, 210, pp. 18-30, (1986)

[5]

Gilbert R.W., Kim J.H., Posner J.B., Epidural spinal cord compression from metastatic tumor: Diagnosis and treatment, Ann Neurol, 3, pp. 40-51, (1978)

[6]

Hall A.J., Mackay N., The results of laminectomy for decompression of the cord or cauda equina by extradural malignant tumor, J Bone Joint Surg, 55B, pp. 497-505, (1973)

[7]

Harrington K.D., The use of methylmethacrylate for vertebral body replacement and anterior stabilization of pathological fracture dislocation of the spine due to metastatic disease, J Bone Joint Surg, 63A, pp. 36-46, (1981)

[8]

Harrington K.D., Metastatic disease of the spine, J Bone Joint Surg, 68A, pp. 1110-1115, (1986)

[9]

Jordan W.E., Shildt R.A., Adenocarcinoma of unknown primary site: The Brooke Army Medical Center experience, Cancer, 55, pp. 857-860, (1985)

[10]

Kaplan E., Meier P., Nonparametric estimation from incomplete observation, American Statistical Association Journal, 53, pp. 457-481, (1958)

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