COMPARISON OF SERIAL PET AND MRI SCANS IN A PEDIATRIC-PATIENT WITH A BRAIN-STEM GLIOMA

被引:30
作者
BRUGGERS, CS
FRIEDMAN, HS
FULLER, GN
TIEN, RD
MARKS, LB
HALPERIN, EC
HOCKENBERGER, B
OAKES, WJ
HOFFMAN, JM
机构
[1] DUKE UNIV,MED CTR,DEPT PATHOL,DURHAM,NC 27710
[2] DUKE UNIV,MED CTR,DEPT RADIOL,DURHAM,NC 27710
[3] DUKE UNIV,MED CTR,DEPT SURG,DURHAM,NC 27710
[4] DUKE UNIV,MED CTR,DEPT RADIAT ONCOL,DURHAM,NC 27710
来源
MEDICAL AND PEDIATRIC ONCOLOGY | 1993年 / 21卷 / 04期
关键词
BRAIN-STEM GLIOMA; PET SCAN; PONTINE GLIOMA;
D O I
10.1002/mpo.2950210414
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Profound clinical deficits may be associated with insults to the brainstem, making management of patients with brainstem gliomas very complex. Small changes in the radiographic appearance of a brainstem tumor may be associated with significant clinical deterioration. Furthermore, both magnetic resonance imaging and computed tomography are frequently unable to differentiate between therapy-related tissue reactions and progressive tumor. Two clinical scenarios particularly difficult to resolve include: (1) transient radiographic and clinical deterioration following hyperfractionated radiotherapy, and (2) clinical deterioration in a patient who has failed initial therapy, but has stable radiographic findings following a second therapy. We report a child with a pontine glioma whose tumor progression was demonstrated more convincingly with a F-18-deoxyglucose positron emission scan than with magnetic resonance imaging. PET scans may be helpful in confirming that tumor progression is responsible for clinical deterioration in a patient whose MRI scans remain stable.
引用
收藏
页码:301 / 306
页数:6
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