INHIBITION OF PROTEIN KINASE-C BY SPHINGOSINE CORRELATES WITH THE PRESENCE OF POSITIVE CHARGE

被引：35

作者：

BOTTEGA, R ^{[1
]}

EPAND, RM ^{[1
]}

BALL, EH ^{[1
]}

机构：

[1] UNIV WESTERN ONTARIO,DEPT BIOCHEM,LONDON N6A 3K7,ONTARIO,CANADA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1989年 / 164卷 / 01期

关键词：

D O I：

10.1016/0006-291X(89)91688-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：102 / 107

页数：6

共 17 条

[1] MECHANISM OF PROTEIN-KINASE-C INHIBITION BY SPHINGOSINE [J].

BAZZI, MD ;

NELSESTUEN, GL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 146 (01) :203-207

[2]

BELL RM, 1988, PROTEIN KINASE C REG, V53, P103

[3] THE RELATIONSHIP BETWEEN THE BILAYER TO HEXAGONAL PHASE-TRANSITION TEMPERATURE IN MEMBRANES AND PROTEIN KINASE-C ACTIVITY [J].

EPAND, RM ;

STAFFORD, AR ;

CHEETHAM, JJ ;

BOTTEGA, R ;

BALL, EH .

BIOSCIENCE REPORTS, 1988, 8 (01) :49-54

[4] THE RELATIONSHIP BETWEEN THE EFFECTS OF DRUGS ON BILAYER STABILITY AND ON PROTEIN-KINASE-C ACTIVITY [J].

EPAND, RM .

CHEMICO-BIOLOGICAL INTERACTIONS, 1987, 63 (03) :239-247

[5]

EPAND RM, 1989, IN PRESS BIOSCIENCE

[6]

HANNUN YA, 1986, J BIOL CHEM, V261, P2604

[7] LYSOSPHINGOLIPIDS INHIBIT PROTEIN-KINASE-C - IMPLICATIONS FOR THE SPHINGOLIPIDOSES [J].

HANNUN, YA ;

BELL, RM .

SCIENCE, 1987, 235 (4789) :670-674

[8]

HANNUN YA, 1987, J BIOL CHEM, V262, P13620

[9]

HANNUN YA, 1985, J BIOL CHEM, V260, P39

[10]

KIKKAWA U, 1983, METHOD ENZYMOL, V99, P288

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