ATTRACTION BETWEEN LIPID BILAYER-MEMBRANES IN CONCENTRATED-SOLUTIONS OF NONADSORBING POLYMERS - COMPARISON OF MEAN-FIELD THEORY WITH MEASUREMENTS OF ADHESION ENERGY

被引：127
作者：
EVANS, E
NEEDHAM, D
机构：
[1] UNIV BRITISH COLUMBIA,DEPT PHYS,VANCOUVER V6T 1W5,BC,CANADA
[2] DUKE UNIV,DEPT MECH ENGN & MAT SCI,DURHAM,NC 27706
来源：
MACROMOLECULES | 1988年 / 21卷 / 06期
关键词：
ADHESION; -; Measurements; LIPIDS; Adhesion; MEMBRANES; Materials; POLYMERS; Solutions;
D O I：
10.1021/ma00184a049
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The authors report direct measurements of the free energy potential for adhesion of synthetic lipid bilayers in aqueous solutions of dextran (polyglucose) over a wide range of volume fraction (0. 01-0. 1) and molecular weight. These polymer solutions are well-modeled by a Flory interaction parameter of 0. 43, characteristic of a 'good' solvent. Controlled assembly of two giant bilayer vesicles was used to evaluate the free energy potential for formation of adhesive contact. The adhesion energy for neutral (phosphatidylcholine) bilayers in 0. 1 M NaCl was found to steadily increase with polymer volume fraction - without any indication of a plateau - and with little dependence of polymer size.
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页码：1822 / 1831
页数：10
相关论文
共 34 条
[1]   CALCULATION OF INTERACTION ENERGY BETWEEN 2 PARALLEL ADSORBING PLANES IMMERSED IN A SOLUTION COMPOSED OF MOLECULES OF DIFFERENT SIZE [J].
ASH, SG ;
FINDENEG.GH .
TRANSACTIONS OF THE FARADAY SOCIETY, 1971, 67 (583) :2122-&
[2]   FREE ENERGY OF A NONUNIFORM SYSTEM .1. INTERFACIAL FREE ENERGY [J].
CAHN, JW ;
HILLIARD, JE .
JOURNAL OF CHEMICAL PHYSICS, 1958, 28 (02) :258-267
[3]  
de Gennes P.G., 1979, SCALING CONCEPTS POL
[4]   POLYMERS AT AN INTERFACE .2. INTERACTION BETWEEN 2 PLATES CARRYING ADSORBED POLYMER LAYERS [J].
DEGENNES, PG .
MACROMOLECULES, 1982, 15 (02) :492-500
[5]   SCALING THEORY OF POLYMER ADSORPTION [J].
DEGENNES, PG .
JOURNAL DE PHYSIQUE, 1976, 37 (12) :1445-1452
[6]   STATISTICAL MECHANICS OF POLYMERS WITH EXCLUDED VOLUME [J].
EDWARDS, SF .
PROCEEDINGS OF THE PHYSICAL SOCIETY OF LONDON, 1965, 85 (546P) :613-&
[7]  
EISENBERG M, 1979, BIOCHEMISTRY, V18, P3213
[8]   FREE-ENERGY POTENTIAL FOR AGGREGATION OF MIXED PHOSPHATIDYLCHOLINE PHOSPHATIDYLSERINE LIPID VESICLES IN GLUCOSE POLYMER (DEXTRAN) SOLUTIONS [J].
EVANS, E ;
METCALFE, M .
BIOPHYSICAL JOURNAL, 1984, 45 (04) :715-720
[9]   PHYSICAL-PROPERTIES OF SURFACTANT BILAYER-MEMBRANES - THERMAL TRANSITIONS, ELASTICITY, RIGIDITY, COHESION, AND COLLOIDAL INTERACTIONS [J].
EVANS, E ;
NEEDHAM, D .
JOURNAL OF PHYSICAL CHEMISTRY, 1987, 91 (16) :4219-4228
[10]   FREE-ENERGY POTENTIAL FOR AGGREGATION OF GIANT, NEUTRAL LIPID BILAYER VESICLES BY VANDERWAALS ATTRACTION [J].
EVANS, E ;
METCALFE, M .
BIOPHYSICAL JOURNAL, 1984, 46 (03) :423-426
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