RELATIONSHIP OF PLASMA CHLORPROMAZINE TO ITS 7-HYDROXY AND SULFOXIDE METABOLITES IN A LARGE POPULATION OF CHRONIC-SCHIZOPHRENICS

被引：127

作者：

MACKAY, AVP ^{[1
]}

HEALEY, AF ^{[1
]}

BAKER, J ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,MRC,DEPT PHARMACOL,NEUROCHEM PHARMACOL UNIT,HILLS RD,CAMBRIDGE CB2 2QD,ENGLAND

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1974年 / 1卷 / 05期

关键词：

D O I：

10.1111/j.1365-2125.1974.tb00281.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：425 / 430

页数：6

共 13 条

[1]

BRODIE BB, 1964, ABSORPTION DISTRIBUT

[2]

COLE JO, 1969, SCHIZOPHRENIC SYNDRO

[3] DETERMINATION OF NANOGRAM QUANTITIES OF CHLORPROMAZINE AND SOME OF ITS METABOLITES IN PLASMA USING GAS-LIQUID CHROMATOGRAPHY WITH AN ELECTRON CAPTURE DETECTOR [J].

CURRY, SH .

ANALYTICAL CHEMISTRY, 1968, 40 (08) :1251-&

[4]

CURRY SH, 1970, ARCH GEN PSYCHIAT, V22, P289

[5]

CURRY SH, 1972, BRIT J PHARMACOL, V44, pP370

[6] CHLORPROMAZINE - CONCENTRATIONS IN PLASMA, EXCRETION IN URINE AND DURATION OF EFFECT [J].

CURRY, SH .

PROCEEDINGS OF THE ROYAL SOCIETY OF MEDICINE-LONDON, 1971, 64 (03) :285-+

[7]

FLINT DR, 1971, CLIN CHEM, V17, P830

[8] CHLORPROMAZINE METABOLISM V - DISPOSITION OF FREE AND CONJUGATED METABOLITES IN BLOOD FRACTIONS OF SCHIZOPHRENIC PATIENTS [J].

KAUL, PN ;

TICKU, MK ;

CLARK, ML .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1972, 61 (11) :1753-&

[9] EFFECT OF VARIOUS CHLORPROMAZINE METABOLITES ON AMPHETAMINE-INDUCED STEREOTYPED BEHAVIOR IN RAT [J].

LAL, S ;

SOURKES, TL .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1972, 17 (02) :283-&

[10]

MANIAN ALBERT A., 1965, LIFE SCI, V4, P2425, DOI 10.1016/0024-3205(65)90298-5

← 1 2 →