THE TREATMENT OF HYPERTENSION - NEW LAMPS FOR OLD

被引：1

作者：

HAMPTON, JR

机构：

[1] Queen's Medical Centre, University Hospital, Nottingham

来源：

CARDIOVASCULAR DRUGS AND THERAPY | 1991年 / 5卷 / 06期

关键词：

HYPERTENSION THERAPY; CLINICAL TRIALS; METAANALYSIS; PRIMARY PREVENTION;

D O I：

10.1007/BF00143524

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Meta-analysis of clinical trials does not help the clinician to treat individual patients. A general conclusion that the reduction of high blood pressure is beneficial has to be matched by specific information about the level of blood pressure that is acceptable and about the effect of particular doses of specific drugs. Results obtained from trials of "old-fashioned" antihypertensive drugs cannot confidently be extrapolated to "modern" agents. Sufficient data do not exist to encourage universal drug treatment for patients with "mild" hypertension.

引用

页码：983 / 985

页数：3

共 20 条

[1]

Collins R., Peto R., MacMahon S., Et al., Blood pressure, stroke, and coronary heart disease. Part 2, short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context, Lancet, 335, pp. 827-838, (1990)

[2]

Cutler J.A., MacMahon S.W., Furberg C.D., Controlled clinical trials of drug treatment for hypertension. A review, Hypertension, 13, pp. I36-I44, (1989)

[3]

Efficacy of antihypertensive drug treatment according to age, sex, blood pressure, and previous cardiovascular disease in patients over the age of 60<sup>*</sup>, Lancet, 2, pp. 589-592, (1986)

[4]

Cameron H.A., Raay L.E., Ketanserin in essential hypertension: a double-blind, placebo-controlled study, Postgrad Med J, 61, pp. 583-586, (1985)

[5]

Prevention of atherosclerotic complications: controlled trial of ketanserin, Br Med J, 298, pp. 424-430, (1989)

[6]

Payer L., Medicine & Culture: Varieties of Treatment in the United States, England, West Germany, and France, (1988)

[7]

MRC trial of treatment of mild hypertension: Principal results, Br Med J, 291, pp. 97-104, (1985)

[8]

McVeigh G., Galloway D., Johnston D., The case for low dose diuretics in hypertension: comparison of low and conventional doses of cyclopenthiazide, Br Med J, 297, pp. 95-97, (1988)

[9]

Mortality and morbidity results from the European Working Party on high blood pressure in the elderly trial, Lancet, 1, pp. 1349-1354, (1985)

[10]

Floras J.S., Jones J.V., Hassan M.O., Et al., Cuff and ambulatory blood pressure in subjects with essential hypertension, Lancet, 2, pp. 107-109, (1981)

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