SYNTHESIS OF 3-ARYLPYRROLES AND 3-PYRROLYLACETYLENES BY PALLADIUM-CATALYZED COUPLING REACTIONS

被引：100
作者：
ALVAREZ, A
GUZMAN, A
RUIZ, A
VELARDE, E
MUCHOWSKI, JM
机构：
[1] SYNTEX INC,INST ORGAN CHEM,3401 HILLVIEW AVE,PALO ALTO,CA 94304
[2] SYNTEX SA,DIV INVEST,MEXICO CITY 10,DF,MEXICO
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 06期
关键词：
D O I：
10.1021/jo00032a011
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Efficacious methods for the synthesis of 3-arylpyrroles or 3-pyrrolylacetylenes are described based on the palladium-catalyzed coupling of appropriate 1-(triisopropylsilyl)-3-substituted pyrroles with aryl halides or monosubstituted acetylenes and subsequent tetrabutylammonium fluoride desilylation.
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页码：1653 / 1656
页数：4
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