A METAANALYSIS OF ALCOHOLIC BEVERAGE CONSUMPTION IN RELATION TO RISK OF COLORECTAL-CANCER

被引：151
作者：
LONGNECKER, MP
ORZA, MJ
ADAMS, ME
VIOQUE, J
CHALMERS, TC
机构：
来源：
CANCER CAUSES & CONTROL | 1990年 / 1卷 / 01期
关键词：
ALCOHOL DRINKING; ALCOHOLIC BEVERAGES; COLORECTAL NEOPLASMS;
D O I：
10.1007/BF00053184
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Quantitative methods were used to review epidemiologic data relating consumption of alcoholic beverages to risk of colorectal cancer. The data (27 studies) supported the presence of a weak association. For consumption of two alcoholic beverages daily, on average the relative risk of colorectal cancer was 1.10 (95% confidence interval 1.05 - 1.14). Other findings were: (1) the association did not vary according to gender or site within the large bowel: (2) results from follow-up studies (relative risk 1.32, 95% confidence interval 1.16 - 1.51) suggested a stronger relationship than those from case-control studies (relative risk 1.07, 95% confidence interval 1.02 - 1.12); and (3) the evidence supporting beverage specificity was not conclusive, although the results were consistent with a stronger association with consumption of beer (relative risk 1.26, 95% confidence interval 1.13 - 1.41) than with consumption of wine (relative risk 1.11, 95% confidence interval 0.91 - 1.36) or liquor (relative risk 1.13, 95% confidence interval 0.99 - 1.29). Because the magnitude of the association between alcohol consumption and risk of colorectal cancer was small, the findings regarding a causal role of alcohol were inconclusive.
引用
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页码：59 / 68
页数：10
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