LEVAMISOLE IN TREATMENT OF ASCARIASIS IN CHILDREN

被引：30

作者：

LIONEL, NDW

MIRANDO, EH

NANAYAKKARA, JC

SOYSA, PE

机构：

[1] Department of Pharmacology, University of Ceylon, Colombo

[2] Lady Ridigeway Hospital, Colombo

[3] Devirtmetit of Paediatrics, University of Ceylon, Colombo

[4] University of Ceylon, Colombo

来源：

BMJ-BRITISH MEDICAL JOURNAL | 1969年 / 4卷 / 5679期

关键词：

D O I：

10.1136/bmj.4.5679.340

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Levamisole (the laevorotatory isomer of tetramisole) is a new synthetic anthelmintic. A cure rate of 91% was obtained in a series of 111 ascariasisinfected children treated with a single oral dose of the drug. The failures, who were treated with the drug a second time one week later, were all cured. In a comparative study of levamisole and piperazine citrate in a series of 100 children with ascariasis a cure rate of 92% and 90% was obtained with a single dose of levamisole and piperazine respectively, indicating equal efficacy. Levamisole is better tolerated than piperazine citrate and is virtually free of toxic effects. © 1969, British Medical Journal Publishing Group. All rights reserved.

引用

页码：340 / +

页数：1

共 9 条

[1]

BEAVER PC, 1961, WHO10 PUBL HEALTH PA, P39

[2]

BULLOCK MW, 1968, J MED CHEM, V11, P169

[3]

FILHA ONDINA BOTELHO do NASCIMENTO, 1966, REV INST MED TROP SAO PAULO, V8, P143

[4]

MESQUITA P. M., 1966, Hospital (Rio de Janeiro, Brazil), V69, P1279

[5]

RAEYMAEKERS AH, 1967, TETRAHEDRON LETT, P1467

[6] COMPARISON OF PIPERAZINE AND TETRAMISOLE IN TREATMENT OF ASCARIASIS [J].

SEFTEL, HC ;

HEINZ, HJ .

BMJ-BRITISH MEDICAL JOURNAL, 1968, 4 (5623) :93-+

[7]

VAN DEN BOSSCHE HUGO, 1967, LIFE SCI, V6, P1781, DOI 10.1016/0024-3205(67)90150-6

[8]

1967, WHO379 TECH REP SER, P47

[9]

1964, WHO277 TECH REP SER

← 1 →