PRIMING ACTION OF ESTROGEN - MINIMUM DURATION OF EXPOSURE FOR FEEDBACK AND BEHAVIORAL-EFFECTS

被引：15

作者：

JOHNSTON, PG ^{[1
]}

DAVIDSON, JM ^{[1
]}

机构：

[1] STANFORD UNIV,DEPT PHYSIOL,STANFORD,CA 94305

来源：

NEUROENDOCRINOLOGY | 1979年 / 28卷 / 03期

关键词：

D O I：

10.1159/000122857

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The minimum duration of the centrally-mediated 'priming' effects of estrogen on 'positive feedback' release of LH and sexual receptivity (lordosis) was studied. Sprayed rats were given Silastic implants of estradiol followed 3 days later by an s.c. injection of progesterone and testing. 30-min implantation of preincubated estradiol capsules sufficed for behavioral responses, but did not stimulate the LH surge. When the capsules were not preincubated, however, LH surges did occur, presumably because of the greater release of estrogen. It is concluded that the minimum duration of the estrogen priming effects is considerably less than the period of natural preovulatory surge of estrogen at proestrus.

引用

页码：155 / 159

页数：5

共 16 条

[1]

BROWNGRANT K, 1972, STEROID HORMONES BRA

[2]

BULLOCK DW, 1970, HORM BEHAV, V1, P137

[3] BIPHASIC EFFECT OF PROGESTERONE ON RELEASE OF GONADOTROPIN IN RATS [J].