FRACTAL DIMENSION OF EXON AND INTRON SEQUENCES

被引：12

作者：

XIAO, Y ^{[1
]}

CHEN, RS ^{[1
]}

SHEN, RQ ^{[1
]}

SUN, J ^{[1
]}

XU, J ^{[1
]}

机构：

[1] ACAD SINICA,INST BIOPHYS,DEPT PROT ENGN,BEIJING 100101,PEOPLES R CHINA

来源：

JOURNAL OF THEORETICAL BIOLOGY | 1995年 / 175卷 / 01期

关键词：

D O I：

10.1006/jtbi.1995.0117

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In this paper, the concept of fractal is applied to describe the features of nucleotide sequences. We introduce the mapping from nucleotide sequences to two-dimensional metric space. Then we use this mapping to study quantitatively the self-similarity of exon and intron sequences in different scales. We find that self-similarity exists in the geometrical range and main range of a nucleotide sequence and define the fractal dimension in these ranges. The results show that the fractal properties of exon sequences are quite different from these of introns, reflecting their difference in structure and function. The fractal dimension of the geometrical range may be used to predict the exon regions of a raw nucleotide sequence. (C) 1995 Academic Press Limited

引用

页码：23 / 26

页数：4