NOVEL METHOD FOR EVALUATING ANTIVIRAL DRUGS AGAINST HUMAN CYTOMEGALOVIRUS IN MICE

被引：13
作者：
ALLEN, LB
LI, SX
ARNETT, G
TOYER, B
SHANNON, WM
HOLLINGSHEAD, MG
机构：
[1] Southern Research Institute, Birmingham, AL 35255
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1992年 / 36卷 / 01期
关键词：
D O I：
10.1128/AAC.36.1.206
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A virus-host cell system in which human cytomegalovirus-infected human cells are entrapped in agarose plugs has been developed. This model provides an inexpensive method for the in vivo evaluation (with outbred, immunocompetent mice) of antiviral drugs against human viruses such as cytomegalovirus that replicate primarily or only in human cells.
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页码：206 / 208
页数：3
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