INFLAMMATORY BOWEL-DISEASE REVISITED - NEWER DRUGS

被引:18
|
作者
HANAUER, SB
机构
[1] University of Chicago Medical Center, Dept. of Medicine, Section of Gastroenterology, Chicago, IL
关键词
5-Aminosalicylic acid; Corticosteroids; Crohn's disease; Cyclosporin; Eicosanoids; Immunosuppressants; Inflammatory bowel disease; Methotrexate; Sulfasalazine; Ulcerative colitis;
D O I
10.3109/00365529009093133
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The development of new drug therapy is an evolutionary process progressing from clinical success with current treatments through an understanding of interactions in the immune and inflammatory events that culminate in the tissue injury of IBD. The basic immunoinflammatory response is reviewed, with identification of the recognized and potential sites of activity of current therapies. Potential sites and implications for future interventions by newer therapies are discussed as we anticipate the discovery of the etiology and eventual cure for ulcerative colitis and Crohn's disease. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
引用
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页码:97 / 106
页数:10
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