A NOTI RESTRICTION MAP OF THE ENTIRE LONG ARM OF HUMAN CHROMOSOME-21

被引：106

作者：

ICHIKAWA, H

HOSODA, F

ARAI, Y

SHIMIZU, K

OHIRA, M

OHKI, M

机构：

[1] Department of Immunology and Virology, Saitama Cancer Center Research Institute, Saitama, 362

来源：

NATURE GENETICS | 1993年 / 4卷 / 04期

关键词：

D O I：

10.1038/ng0893-361

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A variety of maps of the human genome have been constructed, including cloned DNA maps. We have isolated 40 of the 42 NotI sites that exist on the long arm of human chromosome 21, as NotI linking clones and constructed a complete NotI restriction map spanning the entire region. This map, which provides the most reliable ordering and distance estimation in the region from a pericentromeric locus to the terminus, demonstrates the usefulness of linking clone mapping for analysing human chromosomes.

引用

页码：361 / 366

页数：6

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