NEURITE OUTGROWTH ELICITED BY EMBRYONIC CHICK HEART - PARTIAL-PURIFICATION OF THE ACTIVE FACTOR

被引：53

作者：

EBENDAL, T ^{[1
]}

BELEW, M ^{[1
]}

JACOBSON, CO ^{[1
]}

PORATH, J ^{[1
]}

机构：

[1] UNIV UPPSALA,DEPT BIOCHEM,S-75123 UPPSALA,SWEDEN

来源：

NEUROSCIENCE LETTERS | 1979年 / 14卷 / 01期

关键词：

D O I：

10.1016/0304-3940(79)95350-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Chick heart explants stimulate a dense outgrowth of neurites in cocultured spinal, sympathetic and ciliary ganglia. A factor sharing these properties was partially purified by gel filtration of extract prepared from lyophilized 18-day embryonic hearts. The active factor has an apparent molecular weight of roughly 40,000 and is evidently distinct from nerve growth factor (NGF) by stimulating the parasympathetic ciliary neurons and by lack of cross-reactivity with antibodies to NGF. © 1979.

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页码：91 / 95

页数：5

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