REGIOSPECIFIC REPLACEMENT OF FLUORINE BY HYDROGEN IN AN AROMATIC RING INDUCED BY A RARE-EARTH ORGANOMETALLIC

被引：38

作者：

DEACON, GB

FORSYTH, CM

SUN, JH

机构：

[1] Department of Chemistry, Monash University, Clayton

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)79974-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pentafluorobenzoic acid reacts with YbCp(2)(dme) to yield, after hydrolysis, 2,3,4,5-tetrafluorobenzoic acid. Conversion is near quantitative with activated magnesium as a coreductant and there is evidence for catalytic turnover in ytterbium on addition of a cyclopentadiene source. Reduction of 2,6-F2C6H3CO2H to o-FC6H4CO2H and of o-FC6H4CO2H to PhCO(2)H has also been achieved.

引用

页码：1095 / 1098

页数：4

共 7 条

[1]

CALDERAZZO F, 1966, J INORG NUCL CHEM, V24, P987

[2] ORGANOLANTHANIDES .1. BIS(POLYFLUOROPHENYL)YTTERBIUM COMPOUNDS [J].