REGIOSPECIFIC REPLACEMENT OF FLUORINE BY HYDROGEN IN AN AROMATIC RING INDUCED BY A RARE-EARTH ORGANOMETALLIC

被引：38
作者：
DEACON, GB
FORSYTH, CM
SUN, JH
机构：
[1] Department of Chemistry, Monash University, Clayton
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 07期
关键词：
D O I：
10.1016/S0040-4039(00)79974-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Pentafluorobenzoic acid reacts with YbCp(2)(dme) to yield, after hydrolysis, 2,3,4,5-tetrafluorobenzoic acid. Conversion is near quantitative with activated magnesium as a coreductant and there is evidence for catalytic turnover in ytterbium on addition of a cyclopentadiene source. Reduction of 2,6-F2C6H3CO2H to o-FC6H4CO2H and of o-FC6H4CO2H to PhCO(2)H has also been achieved.
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页码：1095 / 1098
页数：4
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