NEW ROUTE FOR THE PREPARATION OF PYRAZOLO[3,4-C]PYRIDINES

被引：5

作者：

MIGLIARA, O

PETRUSO, S

SPRIO, V

机构：

[1] Istituto di Chimica Farmaceutica e Tossicologica, Facoltà di Farmacia, Università, Palermo, 90123, Via Archirafi

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1979年 / 16卷 / 03期

关键词：

D O I：

10.1002/jhet.5570160334

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Catalytic reduction of the oximes of 4‐phenacyl‐3(5)R‐pyrazole‐4‐carboxylic acid esters (4a,b) followed by cyclisalion constitutes a new appraoch to substituted pyrazolo[3,4‐c]pyridines. The starting materials 4a,b were prepared by reaction of ω‐bromoacetophenone oxime and sodium salts of oxalyl derivatives 2a,b and successive action of hydrazine on the obtained products 3a,b. Structural assignments rested upon correct elemental analysis and spectroscopic evidences. Copyright © 1979 Journal of Heterocyclic Chemistry

引用

页码：577 / 579

页数：3

共 15 条

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