THE SULFOXIDE MOIETY OF SUBSTITUTED BENZIMIDAZOLES IS ESSENTIAL FOR INHIBITION OF PARIETAL-CELL K+/H+-ATPASE

被引：7

作者：

BEIL, W

ELTZE, M

HEINTZE, K

KLEMM, K

RIEDEL, R

SCHUDT, C

SEWING, KF

SIMON, A

机构：

[1] HANOVER UNIV MED,ALLGEMEINE PHARMAKOL ABT,D-3000 HANOVER 61,FED REP GER

[2] BYK GULDEN RES LABS,D-7750 KONSTANZ,FED REP GER

来源：

BRITISH JOURNAL OF PHARMACOLOGY | 1986年 / 88卷 / 02期

关键词：

D O I：

10.1111/j.1476-5381.1986.tb10215.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：389 / 395

页数：7

共 50 条

[1] INHIBITION OF GASTRIC-MUCOSAL K+/H+-ATPASE AND PHOSPHODIESTERASE BY SUBSTITUTED BENZIMIDAZOLES
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[2] INHIBITION OF PARTIALLY PURIFIED K+/H+-ATPASE FROM GUINEA-PIG ISOLATED AND ENRICHED PARIETAL-CELLS BY SUBSTITUTED BENZIMIDAZOLES
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[3] SUBSTITUTED BENZIMIDAZOLES, INHIBITORS OF THE K+/H+-ATPASE OF PARIETAL-CELLS - A NEW PRINCIPLE FOR THE TREATMENT OF PEPTIC-ULCER
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[4] EVIDENCE FOR (H+,K+) ATPASE AUTOANTIBODIES IN PATIENTS WITH PARIETAL-CELL IMMUNOREACTIVE SERUM
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[6] CHARACTERISTICS OF K+/H+-ATPASE INHIBITION BY OMEPRAZOLE AND OMEPRAZOLE SULFIDE
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[7] GASTRIC PARIETAL-CELL DEVELOPMENT - EXPRESSION OF THE H+/K+ ATPASE SUBUNITS COINCIDES WITH THE BIOGENESIS OF THE SECRETORY MEMBRANES
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[8] LOCALIZATION OF GASTRIC K+,H+-ATPASE
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[9] EVIDENCE FOR ACID-INDUCED TRANSFORMATION OF OMEPRAZOLE INTO AN ACTIVE INHIBITOR OF (H+ + K+)-ATPASE WITHIN THE PARIETAL-CELL
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[10] K+ CHANNEL IN THE GASTRIC PARIETAL-CELL APICAL MEMBRANE
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