THE INFLUENCE OF BOUNDARY-CONDITIONS ON THE ACCURACY OF DIFFUSION-THEORY IN TIME-RESOLVED REFLECTANCE SPECTROSCOPY OF BIOLOGICAL TISSUES

被引:112
作者
HIELSCHER, AH [1 ]
JACQUES, SL [1 ]
WANG, LH [1 ]
TITTEL, FK [1 ]
机构
[1] UNIV TEXAS,MD ANDERSON CANC CTR,LASER BIOL RES LAB,HOUSTON,TX 77030
关键词
D O I
10.1088/0031-9155/40/11/013
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The applicability of diffusion theory for the determination of tissue optical properties from time-resolved reflectance spectroscopy is investigated. Analytical expressions from diffusion theory using the three most commonly assumed boundary conditions at the air-tissue interface are compared with time-resolved Monte Carlo simulations and measurements on tissue phantoms. The effects of the choice of the boundary conditions on the accuracy of the findings for the optical parameters are quantified, and criteria for accurate curve-fitting algorithms are developed.
引用
收藏
页码:1957 / 1975
页数:19
相关论文
共 34 条
[1]  
Abramowitz M.., 1972, HDB MATH FUNCTIONS
[2]   THE THEORETICAL BASIS FOR THE DETERMINATION OF OPTICAL PATHLENGTHS IN TISSUE - TEMPORAL AND FREQUENCY-ANALYSIS [J].
ARRIDGE, SR ;
COPE, M ;
DELPY, DT .
PHYSICS IN MEDICINE AND BIOLOGY, 1992, 37 (07) :1531-1560
[3]  
AVRAHAM DB, 1991, LASERS LIFE SCI, V4, P29
[4]   NONINVASIVE METHODS FOR ESTIMATING INVIVO OXYGENATION [J].
BENARON, DA ;
BENITZ, WE ;
ARIAGNO, RL ;
STEVENSON, DK .
CLINICAL PEDIATRICS, 1992, 31 (05) :258-273
[5]  
BRIESMEISTER JF, 1986, MCNP GENERAL MONTE C
[6]  
CARSLAW HS, 1959, CONDUCTIOKN HEAT SOL
[7]  
CASE KM, 1967, LINEAR TRANSPORT THE
[8]   COMPARISON OF TIME-RESOLVED AND TIME-UNRESOLVED MEASUREMENTS OF DEOXYHEMOGLOBIN IN BRAIN [J].
CHANCE, B ;
LEIGH, JS ;
MIYAKE, H ;
SMITH, DS ;
NIOKA, S ;
GREENFELD, R ;
FINANDER, M ;
KAUFMANN, K ;
LEVY, W ;
YOUNG, M ;
COHEN, P ;
YOSHIOKA, H ;
BORETSKY, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (14) :4971-4975
[9]   CARDIOVASCULAR APPLICATIONS OF LASER TECHNOLOGY [J].
DECKELBAUM, LI .
LASERS IN SURGERY AND MEDICINE, 1994, 15 (04) :315-341
[10]  
DUDERSTADT JJ, 1976, NUCL REACTOR ANAL, P140