INHIBITION OF THE ACTIVATION OF HAGEMAN-FACTOR (FACTOR-XII) BY APROTININ (TRASYLOL)

被引：0

作者：

LAUREL, MTP ^{[1
]}

RATNOFF, OD ^{[1
]}

EVERSON, B ^{[1
]}

机构：

[1] CASE WESTERN RESERVE UNIV HOSP,SCH MED,DEPT MED HEMATOL,2074 ABINGTON RD,CLEVELAND,OH 44106

来源：

JOURNAL OF LABORATORY AND CLINICAL MEDICINE | 1992年 / 119卷 / 05期

关键词：

D O I：

暂无

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Aprotinin (Trasylol; Bayer AG, Leverkusen, Germany), a protease inhibitor resembling or identical with Kunitz' pancreatic trypsin inhibitor, is said to have anticoagulant properties, but these are not clearly defined. The present study provides evidence that one action of aprotinin is inhibition of the activation of Hageman factor (factor XII).

引用

页码：580 / 585

页数：6

共 23 条

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