EFFICACY OF THE STEROIDAL FRACTION OF FENUGREEK SEED EXTRACT ON FERTILITY OF MALE ALBINO-RATS

被引：20

作者：

KAMAL, R ^{[1
]}

YADAV, R ^{[1
]}

SHARMA, JD ^{[1
]}

机构：

[1] UNIV RAJASTHAN,DEPT ZOOL,REPROD PHYSIOL LAB,JAIPUR 302004,RAJASTHAN,INDIA

来源：

PHYTOTHERAPY RESEARCH | 1993年 / 7卷 / 02期

关键词：

TRIGONELLA-FOENUM-GRAECUM; STEROIDAL SAPOGENIN; RATTUS-NORVEGICUS; SPERM MOTILITY; SPERMATOGENESIS; ANTIFERTILITY;

D O I：

10.1002/ptr.2650070208

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

T. foenum-graecum seed extract (100 mg/day/rat) was fed orally to male albino rats for 60 days. The sperm count and motility of cauda spermatozoa declined significantly leading to negative fertility tests. The organ weights as well as androgen dependent parameters (protein, sialic acid and fructose) were lower, revealing the reduction in circulating androgen. Cholesterol is a precursor of androgen. The increase in testicular and serum cholesterol may be co-related with its nonutilization by the system, leading to a fall in circulating androgen and hence the altered histoarchitecture observed. Therefore T. foenum-graecum extract exerts both antifertility and antiandrogenic activities.

引用

页码：134 / 138

页数：5

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