IMPORTANCE OF DIETARY CHLORIDE FOR SALT SENSITIVITY OF BLOOD-PRESSURE

被引：38

作者：

BOEGEHOLD, MA ^{[1
]}

KOTCHEN, TA ^{[1
]}

机构：

[1] W VIRGINIA UNIV, MED CTR,SCH MED,DEPT MED,HLTH SCI CTR N, MORGANTOWN, WV 26506 USA

来源：

HYPERTENSION | 1991年 / 17卷 / 01期

关键词：

NACL-DEPENDENT HYPERTENSION; SODIUM CHLORIDE; CHLORIDES; DEOXYCORTICOSTERONE; BLOOD PRESSURE; DAHL RATS;

D O I：

10.1161/01.HYP.17.1_Suppl.I158

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Recent evidence indicates that the anion accompanying sodium plays an important role in determining the magnitude of the blood pressure increase in response to a high dietary intake of NaCl. The purpose of this review is to describe studies of blood pressure responses to selective dietary sodium loading (without chloride) and to selective dietary chloride loading (without sodium) in several experimental models of salt-sensitive hypertension and in hypertensive humans. The full expression of salt sensitivity depends on high dietary intakes of both sodium and chloride. This observation has implications for understanding mechanisms contributing to NaCl-induced hypertension.

引用

页码：I158 / I161

页数：4

共 26 条

[1]

Berghoff RS, 1929, IMJ, V56, P395

[2] SYMPATHETIC HYPERACTIVITY ELEVATES BLOOD-PRESSURE DURING ACUTE CEREBROVENTRICULAR INFUSIONS OF HYPERTONIC SALT IN RATS [J].

BUNAG, RD ;

MIYAJIMA, E .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1984, 6 (05) :844-851

[3] THE RELATION OF SERUM BICARBONATE CONCENTRATION TO MUSCLE COMPOSITION [J].

DARROW, DC ;

SCHWARTZ, R ;

IANNUCCI, JF ;

COVILLE, F .

JOURNAL OF CLINICAL INVESTIGATION, 1948, 27 (02) :198-208

[4] DIETARY TREATMENT OF HYPERTENSION - CLINICAL AND METABOLIC STUDIES OF PATIENTS ON THE RICE-FRUIT DIET [J].

DOLE, VP ;

DAHL, LK ;

COTZIAS, GC ;

EDER, HA ;

KREBS, ME .

JOURNAL OF CLINICAL INVESTIGATION, 1950, 29 (09) :1189-1206

[5] HOW DOES SALT RAISE BLOOD-PRESSURE - A HYPOTHESIS [J].

GAVRAS, H .

HYPERTENSION, 1986, 8 (01) :83-88

[6] FAILURE OF SALT LOADING TO INHIBIT TISSUE NOREPINEPHRINE TURNOVER IN PREHYPERTENSIVE DAHL SALT-SENSITIVE RATS [J].

GENAIN, CP ;

REDDY, SR ;

OTT, CE ;

VANLOON, GR ;

KOTCHEN, TA .

HYPERTENSION, 1988, 12 (06) :568-573

[7] SODIUM RESTRICTION IN THE DIET FOR HYPERTENSION [J].

GROLLMAN, A ;

HARRISON, TR ;

MASON, MF ;

BAXTER, J ;

CRAMPTON, J ;

REICHSMAN, F .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1945, 129 (08) :533-537

[8] NEURO-HORMONAL CHARACTERISTICS OF CARDIOVASCULAR-RESPONSE DUE TO INTRAVENTRICULAR HYPERTONIC NACL [J].

KAWANO, Y ;

FERRARIO, CM .

AMERICAN JOURNAL OF PHYSIOLOGY, 1984, 247 (03) :H422-H428

[9] EFFECT OF CHLORIDE ON RENIN AND BLOOD-PRESSURE RESPONSES TO SODIUM-CHLORIDE [J].

KOTCHEN, TA ;

LUKE, RG ;

OTT, CE ;

GALLA, JH ;

WHITESCARVER, S .

ANNALS OF INTERNAL MEDICINE, 1983, 98 (05) :817-822

[10] CALCIUM AND CALCIUM REGULATING HORMONES IN THE PREHYPERTENSIVE DAHL SALT SENSITIVE RAT (CALCIUM AND SALT SENSITIVE HYPERTENSION) [J].

KOTCHEN, TA ;

OTT, CE ;

WHITESCARVER, SA ;

RESNICK, LM ;

GERTNER, JM ;

BLEHSCHMIDT, NG .

AMERICAN JOURNAL OF HYPERTENSION, 1989, 2 (10) :747-753

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