Overhydration measured by bioimpedance analysis and the survival of patients on maintenance hemodialysis: a single-center study

被引：66

作者：

Kim, Ye Jin ^{[1
]}

Jeon, Hong Jae ^{[1
]}

Kim, Yoo Hyung ^{[1
]}

Jeon, Jaewoong ^{[1
]}

Ham, Young Rok ^{[1
]}

Chung, Sarah ^{[1
]}

Choi, Dae Eun ^{[1
]}

Na, Ki Ryang ^{[1
]}

Lee, Kang Wook ^{[1
]}

机构：

[1] Chungnam Natl Univ Hosp, Dept Internal Med, 282 Munwharo, Daejeon 35015, South Korea

来源：

KIDNEY RESEARCH AND CLINICAL PRACTICE | 2015年 / 34卷 / 04期

关键词：

Bioimpedance analysis; Extracellular water; Hemodialysis; Hydration; Mortality;

D O I：

10.1016/j.krcp.2015.10.006

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Bioimpedance analysis (BIA) helps measuring the constituents of the body noninvasively. Prior studies suggest that BIA-guided fluid assessment helps to predict survival in dialysis patients. We aimed to evaluate the clinical usefulness of BIA for predicting the survival rate of hemodialysis patients in Korea. Methods: We conducted a single-center retrospective study. All patients were diagnosed with end-stage renal disorder and started maintenance hemodialysis between June 2009 and April 2014. BIA was performed within the 1st week from the start of hemodialysis. The patients were classified into 2 groups based on volume status measured by the body composition monitor (BCM; Fresenius): an overhydrated group [OG; overhydration/extracellular water (OH/ECW) > 15%] and a nonoverhydrated group (NOG; OH/ECW <= 15%). Results: A total of 344 patients met the inclusion criteria. Of these, 252 patients (73.3%) were categorized into the OG and 92 patients (26.7%) into the NOG. Age-and sex-matching patients were selected with a rate of 2: 1. Finally, 160 overhydrated patients and 80 nonoverhydrated patients were analyzed. Initial levels of hemoglobin and serum albumin were significantly lower in the OG. During follow-up, 43 patients from the OG and 7 patients from the NOG died (median follow-up duration, 24.0 months). The multivariate-adjusted all-cause mortality was significantly increased in the OG (odds ratio, 2.569; P = 0.033) and older patients (odds ratio, 1.072/y; P < 0.001). No significant difference of all-cause or disease-specific admission rate was observed between the 2 groups. Conclusion: The ratio of OH/ECW volume measured with body composition monitor is related to the overall survival of end-stage renal disorder patients who started maintenance hemodialysis. (C) 2015. The Korean Society of Nephrology. Published by Elsevier. This is an open access article under the CC BY-NC-ND license.

引用

页码：212 / 218

页数：7

共 40 条

[1] Equivalence of the bioimpedance and thermodilution methods in measuring cardiac output in hospitalized patients with advanced, decompensated chronic heart failure [J].