ON THE USE OF COMBINATORIAL ANTIBODY LIBRARIES TO CLONE THE FOSSIL RECORD OF AN INDIVIDUALS IMMUNE-RESPONSE

被引：22

作者：

LERNER, RA ^{[1
]}

BARBAS, CF ^{[1
]}

KANG, AS ^{[1
]}

BURTON, DR ^{[1
]}

机构：

[1] SCRIPPS RES INST, DEPT MOLEC BIOL, LA JOLLA, CA 92037 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1991年 / 88卷 / 21期

关键词：

PASSIVE ANTIBODY; AIDS; IMMUNOLOGICAL MEMORY; CATALYTIC ANTIBODIES;

D O I：

10.1073/pnas.88.21.9705

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

For about the last century the record of immunological events could only be obtained from serum proteins. We suggest that in the future this will change and the far more detailed nucleic acid record will provide new insights into immunological processes as well as selective access to the complete repertoire.

引用

页码：9705 / 9706

页数：2

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