CHARYBDOTOXIN BLOCKS CATION-CHANNELS IN THE VACUOLAR MEMBRANE OF SUSPENSION CELLS OF CHENOPODIUM-RUBRUM L

被引：10

作者：

WEISER, T

BENTRUP, FW

机构：

[1] Botanisches Institut der Justus-Liebig-Universität, Giessen

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1991年 / 1066卷 / 01期

关键词：

CATION CHANNEL; CHARYBDOTOXIN; VACUOLAR MEMBRANE; TONOPLAST; PATCH-CLAMP TECHNIQUE; (CHENOPODIUM-RUBRUM);

D O I：

10.1016/0005-2736(91)90258-A

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Using the patch-clamp technique, we studied the action of charybdotoxin which blocks Ca2+-activated large-conductance K+ channels in animal tissue on the slow-activating (SV), Ca2+-activated cation channel in the vacuolar membrane of suspension-cells of Chenopodium rubrum L. The toxin reversibly reduced the vacuolar current with EC50 almost-equal-to 20 nM suggesting structural similarities between ion channels in animal and plant membranes.

引用

页码：109 / 110

页数：2

共 6 条

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[3] CHARYBDOTOXIN, A PROTEIN INHIBITOR OF SINGLE CA-2(+)-ACTIVATED K+ CHANNELS FROM MAMMALIAN SKELETAL-MUSCLE
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LATORRE, R
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[5] (+)-TUBOCURARINE IS A POTENT INHIBITOR OF CATION CHANNELS IN THE VACUOLAR MEMBRANE OF CHENOPODIUM-RUBRUM L
WEISER, T
BENTRUP, FW
[J]. FEBS LETTERS, 1990, 277 (1-2) : 220 - 222
[6] WEISER T, 1991, IN PRESS PLANTA

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