ISOLATION OF A NEW DIARRHETIC SHELLFISH POISON FROM IRISH MUSSELS

被引：104
作者：
HU, TM
DOYLE, J
JACKSON, D
MARR, J
NIXON, E
PLEASANCE, S
QUILLIAM, MA
WALTER, JA
WRIGHT, JLC
机构：
[1] NATL RES COUNCIL CANADA,ATLANTIC REG LAB,INST MARINE BIOSCI,1411 OXFORD ST,HALIFAX B3H 3Z1,NS,CANADA
[2] FENWICK LABS LTD,HALIFAX B3H 4M2,NS,CANADA
[3] DEPT MARINE FISHERIES RES CTR,DUBLIN 15,IRELAND
[4] SCIEX INC,THORNHILL L3T 1P2,ONTARIO,CANADA
来源：
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 01期
关键词：
D O I：
10.1039/c39920000039
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new marine toxin dinophysistoxin-2 (DTX-2) 4, isolated from toxic Irish mussels and biogenetically related to the toxins okadaic acid 1 and dinophysistoxin-1 (DTX-1) 2, the principal agents responsible for diarrhetic shellfish poisoning (DSP), is reported.
引用
收藏
页码：39 / 41
页数：3
相关论文
共 10 条
[1]   OKADAIC ACID - A NEW PROBE FOR THE STUDY OF CELLULAR-REGULATION [J].
COHEN, P ;
HOLMES, CFB ;
TSUKITANI, Y .
TRENDS IN BIOCHEMICAL SCIENCES, 1990, 15 (03) :98-102
[2]   IDENTIFICATION OF OKADAIC ACID FROM A CARIBBEAN DINOFLAGELLATE, PROROCENTRUM-CONCAVUM [J].
DICKEY, RW ;
BOBZIN, SC ;
FAULKNER, DJ ;
BENCSATH, FA ;
ANDRZEJEWSKI, D .
TOXICON, 1990, 28 (04) :371-377
[3]   INHIBITION OF PROTEIN PHOSPHATASE-1 AND PHOSPHATASE-2A WITH ACANTHIFOLICIN - COMPARISON WITH DIARRHETIC SHELLFISH TOXINS AND IDENTIFICATION OF A REGION ON OKADAIC ACID IMPORTANT FOR PHOSPHATASE INHIBITION [J].
HOLMES, CFB ;
LUU, HA ;
CARRIER, F ;
SCHMITZ, FJ .
FEBS LETTERS, 1990, 270 (1-2) :216-218
[4]  
KAT M, 1983, A VAN LEEUW J MICROB, V49, P417
[5]   Determination of diarrhetic shellfish toxins in various dinoflagellate species [J].
Lee, Jong-Soo ;
Igarashi, Teruo ;
Fraga, Santiago ;
Dahl, Einal ;
Hovgaard, Peter ;
Yasumotol, Takeshi .
JOURNAL OF APPLIED PHYCOLOGY, 1989, 1 (02) :147-152
[6]   FLUOROMETRIC-DETERMINATION OF DIARRHETIC SHELLFISH TOXINS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].
LEE, JS ;
YANAGI, T ;
KENMA, R ;
YASUMOTO, T .
AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1987, 51 (03) :877-881
[7]  
MURATA M, 1982, B JPN SOC SCI FISH, V48, P549
[8]   ION-SPRAY MASS-SPECTROMETRY OF MARINE TOXINS .2. ANALYSIS OF DIARRHETIC SHELLFISH TOXINS IN PLANKTON BY LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY [J].
PLEASANCE, S ;
QUILLIAM, MA ;
DEFREITAS, ASW ;
MARR, JC ;
CEMBELLA, AD .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1990, 4 (06) :206-213
[9]   OKADAIC ACID, A CYTO-TOXIC POLYETHER FROM 2 MARINE SPONGES OF THE GENUS HALICHONDRIA [J].
TACHIBANA, K ;
SCHEUER, PJ ;
TSUKITANI, Y ;
KIKUCHI, H ;
VANENGEN, D ;
CLARDY, J ;
GOPICHAND, Y ;
SCHMITZ, FJ .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (09) :2469-2471
[10]   DIARRHETIC SHELLFISH TOXINS [J].
YASUMOTO, T ;
MURATA, M ;
OSHIMA, Y ;
SANO, M ;
MATSUMOTO, GK ;
CLARDY, J .
TETRAHEDRON, 1985, 41 (06) :1019-1025
1