KINETIC RESOLUTION OF RACEMIC ALCOHOLS WITH CHIRAL CARBOXYLIC-ACIDS AND DICYCLOHEXYLCARBODIIMIDE

被引：28

作者：

CHINCHILLA, R

NAJERA, C

YUS, M

HEUMANN, A

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,E-03690 ALACANT,SPAIN

[2] UNIV AIX MARSEILLE,CTR ST JEROME,ENSSPICAM,URA 1410,F-13013 MARSEILLE,FRANCE

来源：

TETRAHEDRON-ASYMMETRY | 1990年 / 1卷 / 12期

关键词：

D O I：

10.1016/S0957-4166(00)82271-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The DCC-esterification method has been used to kinetically resolve racemic mixtures of alcohols. With simple chiral carboxylic acids, such as O-aryl lactic acids, in the presence of various basic catalysts, mixtures of the enantiomerically enriched alcohols (e.e. < 50%) and the corresponding esters (d.e. < 70%) have been obtained.

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页码：851 / 854

页数：4

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