PRESENCE OF D-ASPARTATE OXIDASE AND FREE D-ASPARTATE IN AMPHIBIAN (XENOPUS-LAEVIS, CYNOPS-PYRRHOGASTER) TISSUES

被引：25

作者：

KERA, Y ^{[1
]}

NAGASAKI, H ^{[1
]}

IWASHIMA, A ^{[1
]}

YAMADA, RH ^{[1
]}

机构：

[1] KYOTO PREFECTURAL UNIV MED, DEPT BIOCHEM, KYOTO 602, JAPAN

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1992年 / 103卷 / 02期

关键词：

D O I：

10.1016/0305-0491(92)90302-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. This paper is the first report on the presence Of D-aspartate oxidase activity and free D-aspartate in the amphibian tissues. 2. The presence of D-aspartate oxidase activity in tissues of clawed toad (Xenopus laevis) and Japanese newt (Cynops pyrrhogaster) was demonstrated by requirements for enzyme activity, selective inhibition with meso-tartrate and substrate specificity. 3. In each animal, the highest activity was found in kidney, followed by liver and brain, and no gender difference in the specific activity was observed in each tissue. 4. A small but significant amount Of D-aspartate was detected in liver and kidney, irrespective of species. 5. In the newt, there was a gender difference in the hepatic and renal content of D-aspartate and not in the D-/D + L-aspartate ratio.

引用

页码：345 / 348

页数：4

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