AN IMPROVED METHOD FOR THE PREPARATION OF DESOXOPEPTIDES - REDUCTIONS OF ENDOTHIOPEPTIDES

被引：38

作者：

GUZIEC, FS

WASMUND, LM

机构：

[1] Department of Chemistry, New Mexico State University, Las Cruces

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 01期

关键词：

D O I：

10.1016/S0040-4039(00)94324-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new procedures for the synthesis of desoxopeptides from endothiopeptides are reported: 1) Raney nickel desulfurizafion, 2) alkylation with triethyloxonium tetrafluoroborate followed by sodium borohydride reduction, and 3) nickel boride reduction. Of these three, reduction with nickel boride was found to be superior due to high yields, reproducibility and convenience. © 1990.

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页码：23 / 26

页数：4

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