Calcium and Vitamin D Supplementation in Men

被引：6
作者：
Gielen, Evelien [1 ,2 ,3 ]
Boonen, Steven [1 ,2 ,3 ]
Vanderschueren, Dirk [3 ,4 ]
Sinnesael, Mieke [4 ]
Verstuyf, Annemieke [4 ]
Claessens, Frank [5 ]
Milisen, Koen [1 ,6 ]
Verschueren, Sabine [7 ]
机构：
[1] Leuven Univ Hosp, Div Geriatr Med, Herestraat 49, B-3000 Leuven, Belgium
[2] Katholieke Univ Leuven, Dept Expt Med, Gerontol & Geriatr Sect, B-3000 Leuven, Belgium
[3] Leuven Univ, Ctr Metab Bone Dis, B-3000 Leuven, Belgium
[4] Katholieke Univ Leuven, Dept Expt Med, Expt Med & Endocrinol, B-3000 Leuven, Belgium
[5] Katholieke Univ Leuven, Dept Mol Cell Biol, Mol Endocrinol Lab, B-3000 Leuven, Belgium
[6] Katholieke Univ Leuven, Ctr Hlth Serv & Nursing Res, B-3000 Leuven, Belgium
[7] Katholieke Univ Leuven, Res Ctr Musculoskeletal Rehabil, Dept Rehabil Sci, B-3000 Leuven, Belgium
来源：
JOURNAL OF OSTEOPOROSIS | 2011年 / 2011卷
关键词：
D O I：
10.4061/2011/875249
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Calcium and vitamin D supplements reverse secondary hyperparathyroidism and are widely prescribed to prevent osteoporotic fractures, with proven antifracture efficacy when targeted to individuals with documented insufficiencies. Men who should particularly be considered for calcium and vitamin D supplements include elderly or institutionalized individuals, patients with documented osteoporosis on antiresorptive or anabolic medication, and individuals receiving glucocorticoids. Benefits are most apparent when a daily dose of 1000-1200 mg calcium is complemented with 800 IU vitamin D. Compliance is the key to optimizing clinical efficacy. While (conventionally dosed) vitamin D has not been associated with safety concerns, recent meta-analytic data have provided evidence to suggest that calcium supplements (without coadministered vitamin D) may potentially be associated with cardiovascular risks.
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页数：6
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