T-CELL ANTIGEN RECEPTOR IMMUNE-COMPLEXES DEMONSTRATING BIOLOGIC AND PROTEOLYTIC ACTIVITY

被引：12

作者：

BRISTOW, CL ^{[1
]}

FLOOD, PM ^{[1
]}

机构：

[1] UNIV N CAROLINA,SCH DENT,DEPT PERIODONT,CHAPEL HILL,NC 27599

来源：

INTERNATIONAL IMMUNOLOGY | 1993年 / 5卷 / 01期

关键词：

ELASTASE; IMMUNE RESPONSIVENESS; ALPHA-1-PROTEASE INHIBITOR;

D O I：

10.1093/intimm/5.1.79

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

An elastase-like protease, recently recognized as a specific product of murine T cells, may functionally associate with the classical TCR. T cell elastase, found in combination with the natural elastase inhibitor alpha1-antitrypsin (alpha1-protease inhibitor, alpha1-PI), is produced by both CD4+ and CD8+ T lymphocytes. T cell elastase and alpha1-PI are found chemically associated with the TCR in an antigen-specific complex reminiscent of the Ig-complement 'immune complexes'.

引用

页码：79 / 88

页数：10

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