Histopathological Variants of Cutaneous Squamous Cell Carcinoma: A Review

被引：119

作者：

Yanofsky, Valerie R. ^{[1
]}

Mercer, Stephen E. ^{[2
]}

Phelps, Robert G. ^{[2
]}

机构：

[1] Albert Einstein Coll Med, Bronx, NY 10461 USA

[2] Mt Sinai Sch Med, Div Dermatopathol, One Gustave L Levy Pl, New York, NY 10029 USA

来源：

JOURNAL OF SKIN CANCER | 2011年 / 2011卷

关键词：

D O I：

10.1155/2011/210813

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Nonmelanoma skin cancer (NMSC) is the most common form of cancer in the Caucasian population, with squamous cell carcinoma (SCC) accounting for the majority of NMSC-related metastases and death. While most SCC lesions are indolent tumors with lowmalignant potential, a wide diversity of SCC subtypes exist, several of which are associated withmarkedlymore aggressive behaviors. Distinguishing these high-risk variants from their counterparts is possible through microscopic analysis, since each subtype possesses unique histopathological features. Early identification of high-risk lesions can allow for more rapid therapeutic intervention, reducing the likelihood of metastasis and death. The authors review specific histopathological features and associated clinical outcomes of the primary subdivisions of SCC.

引用

页数：13

共 83 条

[1]

ACKERMAN LV, 1948, SURGERY, V23, P670

[2] High incidence and clinical course of aggressive skin cancer in heart transplant patients: A single-center study [J].