Serum leptin levels among malnourished children with and without pneumonia

被引：2

作者：

Al Biltagi, Mohammed ^{[1
]}

Baset, Ahmed Abdul ^{[1
]}

Hagag, Adel ^{[1
]}

Al Srogi, Hesham ^{[2
]}

机构：

[1] Tanta Univ, Fac Med, Pediat Dept, Tanta, Egypt

[2] Tanta Univ, Fac Med, Clin Pathol Dept, Tanta, Egypt

来源：

JOURNAL OF PEDIATRIC BIOCHEMISTRY | 2010年 / 1卷 / 03期

关键词：

Protein-energy malnutrition; leptin; CD4%; marasmus; kwashiorkor;

D O I：

10.3233/JPB-2010-0021

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The aim was to evaluate the serum leptin level in children with protein-energy malnutrition (PEM) with and without pneumonia. The study included 60 children; 20 were controls, 20 had PEM without infection and 20 had PEM and pneumonia. They were subjected to nutritional assessments; serum leptin level, haemoglobin concentration, white-blood cell (WBC) count, CD4%, serum albumin, blood glucose, blood urea-nitrogen, and serum ferritin, and chest x-ray. Serum leptin levels were independently associated with pneumonia on multivariate analysis. In addition, serum leptin level and CD4% were significantly lower in the groups with PEM and pneumonia than in the group with PEM without pneumonia (p < 0.001). Low serum leptin levels were associated with pneumonia in children with protein energy malnutrition.

引用

页码：209 / 215

页数：7

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