THE MLLT3 GENE MAPS BETWEEN D9S156 AND D9S171 AND CONTAINS AN UNSTABLE POLYMORPHIC TRINUCLEOTIDE REPEAT

被引：9

作者：

WALKER, GJ ^{[1
]}

WALTERS, MK ^{[1
]}

PALMER, JM ^{[1
]}

HAYWARD, NK ^{[1
]}

机构：

[1] QUEENSLAND INST MED RES,JOINT EXPTL ONCOL PROGRAM,QUEENSLAND CANC FUND,RES UNIT,HERSTON,QLD 4029,AUSTRALIA

来源：

GENOMICS | 1994年 / 20卷 / 03期

关键词：

D O I：

10.1006/geno.1994.1206

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

MLLT3, one of the genes shown to be a translocation breakpoint partner for the acute lymphocytic leukemia (MLL) gene, has been mapped to 9p22. me have identified a polymorphic trinucleotide repeat within this gene that shows somatic instability. The inheritance pattern of this polymorphism in recombinant individuals from families previously typed for other chromosome 9 markers indicates that the gene lies in the interval bounded by D9S156 and D9S171. (C) 1993 Academic Press, Inc.

引用

收藏

页码：490 / 491

页数：2

相关论文

共 12 条

[1] CLUES TO THE PATHOGENESIS OF FAMILIAL COLORECTAL-CANCER [J].

AALTONEN, LA ;

PELTOMAKI, P ;

LEACH, FS ;

SISTONEN, P ;

PYLKKANEN, L ;

MECKLIN, JP ;

JARVINEN, H ;

POWELL, SM ;

JEN, J ;

HAMILTON, SR ;

PETERSEN, GM ;

KINZLER, KW ;

VOGELSTEIN, B ;

DELACHAPELLE, A .

SCIENCE, 1993, 260 (5109) :812-816

[2] HOMOZYGOUS DELETIONS WITHIN HUMAN-CHROMOSOME BAND-9P21 IN MELANOMA [J].

FOUNTAIN, JW ;

KARAYIORGOU, M ;

ERNSTOFF, MS ;

KIRKWOOD, JM ;

VLOCK, DR ;

TITUSERNSTOFF, L ;

BOUCHARD, B ;

VIJAYASARADHI, S ;

HOUGHTON, AN ;

LAHTI, J ;

KIDD, VJ ;

HOUSMAN, DE ;

DRACOPOLI, NC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (21) :10557-10561

[3] THE T(4-11) CHROMOSOME-TRANSLOCATION OF HUMAN ACUTE LEUKEMIAS FUSES THE ALL-1 GENE, RELATED TO DROSOPHILA-TRITHORAX, TO THE AF-4 GENE [J].

GU, Y ;

NAKAMURA, T ;

ALDER, H ;

PRASAD, R ;

CANAANI, O ;

CIMINO, G ;

CROCE, CM ;

CANAANI, E .

CELL, 1992, 71 (04) :701-708

[4] UBIQUITOUS SOMATIC MUTATIONS IN SIMPLE REPEATED SEQUENCES REVEAL A NEW MECHANISM FOR COLONIC CARCINOGENESIS [J].

IONOV, Y ;

PEINADO, MA ;

MALKHOSYAN, S ;

SHIBATA, D ;

PERUCHO, M .

NATURE, 1993, 363 (6429) :558-561

[5]

KWIATKOWSKI DJ, 1993, CYTOGENET CELL GENET, V64, P94

[6] A POLYMORPHIC X-LINKED TETRANUCLEOTIDE REPEAT LOCUS DISPLAYING A HIGH-RATE OF NEW MUTATION - IMPLICATIONS FOR MECHANISMS OF MUTATION AT SHORT TANDEM REPEAT LOCI [J].

MAHTANI, MM ;

WILLARD, HF .

HUMAN MOLECULAR GENETICS, 1993, 2 (04) :431-437

[7] GENES ON CHROMOSOME-4, CHROMOSOME-9, AND CHROMOSOME-19 INVOLVED IN 11Q23 ABNORMALITIES IN ACUTE-LEUKEMIA SHARE SEQUENCE HOMOLOGY AND OR COMMON MOTIFS [J].

NAKAMURA, T ;

ALDER, H ;

GU, Y ;

PRASAD, R ;

CANAANI, O ;

KAMADA, N ;

GALE, RP ;

LANGE, B ;

CRIST, WM ;

NOWELL, PC ;

CROCE, CM ;

CANAANI, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (10) :4631-4635

[8] TRINUCLEOTIDE REPEAT INSTABILITY - WHEN AND WHERE [J].

NELSON, DL ;

WARREN, ST .

NATURE GENETICS, 1993, 4 (02) :107-108

[9] MICROSATELLITE INSTABILITY IN CANCER OF THE PROXIMAL COLON [J].

THIBODEAU, SN ;

BREN, G ;

SCHAID, D .

SCIENCE, 1993, 260 (5109) :816-819

[10] INVOLVEMENT OF A HOMOLOG OF DROSOPHILA-TRITHORAX BY 11Q23 CHROMOSOMAL TRANSLOCATIONS IN ACUTE LEUKEMIAS [J].

TKACHUK, DC ;

KOHLER, S ;

CLEARY, ML .

CELL, 1992, 71 (04) :691-700