DELTA-9-TETRAHYDROCANNABINOL SHOWS ANTISPASTIC AND ANALGESIC EFFECTS IN A SINGLE CASE DOUBLE-BLIND TRIAL

被引：81
作者：
MAURER, M
HENN, V
DITTRICH, A
HOFMANN, A
机构：
[1] UNIV ZURICH,NEUROL KLIN & POLIKLIN,FRAUENKLIN STR 26,CH-8006 ZURICH,SWITZERLAND
[2] PSYCHOL INST BERATUNG & FORSCHUNG,PSIN,CH-8032 ZURICH,SWITZERLAND
[3] UNIV ZURICH,INST PHARMAKOL,CH-8006 ZURICH,SWITZERLAND
来源：
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE | 1990年 / 240卷 / 01期
关键词：
Analgesia; Delta-9-tetrahydrocannabinol; Spasticity; Spinal cord injury;
D O I：
10.1007/BF02190083
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A double-blind study was performed comparing 5 mg delta-9-tetrahydrocannabinol (THC) p.o., 50 mg codeine p.o., and placebo in a patient with spasticity and pain due to spinal cord injury. The three conditions were applied 18 times each in a randomized and balanced order. Delta-9-THC and codeine both had an analgesic effect in comparison with placebo. Only delta-9-THC showed a significant beneficial effect on spasticity. In the dosage of THC used no altered consciousness occurred. © 1990 Springer-Verlag.
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页码：1 / 4
页数：4
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