VARIOUS FACTORS INFLUENCING THE SIGNAL INTENSITY OF OLIGONUCLEOTIDES IN ELECTROSPRAY MASS-SPECTROMETRY

被引:81
作者
BLEICHER, K [1 ]
BAYER, E [1 ]
机构
[1] UNIV TUBINGEN,INST ORGAN CHEM,D-72076 TUBINGEN,GERMANY
关键词
D O I
10.1002/bms.1200230604
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The quality of electrospray mass spectra of oligonucleotides often suffers from the low signal intensity and clustering with metal ions. This sometimes makes an exact determination of the molecular masses impossible. We describe here several factors contributing to these effects and show some means for their improvement.
引用
收藏
页码:320 / 322
页数:3
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